Karin Gallandat | Riley C. Kolus | Timothy R. Julian | Daniele S. Lantagne
Date of Publication:
May 19, 2020
American Journal of Infection Control
Infectious diseases can be transmitted via fomites (contaminated surfaces/objects); disinfection can interrupt this transmission route. However, disinfection guidelines for low-resource outbreak settings are inconsistent and not evidence-based. A systematic review of surface disinfection efficacy studies was conducted to inform low-resource outbreak guideline development.
Data were extracted from 89 laboratory studies and made available, including 20 studies on relevant pathogens used in combination with surrogate data to determine minimum target concentration × time factors. Stainless steel (68%) and chlorine-based disinfectants (56%) were most commonly tested. No consistent trend was seen in the influence of chlorine concentration and exposure time on disinfection efficacy. Disinfectant application mode; soil load; and surface type were frequently identified as influential factors in included studies.
This review highlights that surface disinfection efficacy estimates are strongly influenced by each study’s experimental conditions. We therefore recommend laboratory testing to be followed by field-based testing/monitoring to ensure effectiveness is achieved in situ.